🔐 Built on robust security protocols, leveraging Monero (XMR) for completeprivacy and anonymous transactions. Our platform is designed with modularsecurity, DDoS resistance, and user privacy at its core. The facilities, which the province is calling HART hubs, are part of the Progressive Conservative government’s marked shift away from harm reduction policies and toward a focus on addictions treatment and recovery. With Philadelphia a long-established pharma hotspot and Pittsburgh an emerging one, Pennsylvania’s life sciences sector employs 100,000 workers across nearly 3,100 companies that have secured more than 10,700 new life sciences patents over the past five years. In early 2025, the company broke ground on a $2 billion manufacturing facility project in Wilson.
Am I likely to get cancer?
The partnership aims to discover and develop new therapeutics, while also forging collaborations with academic and research institutions in the UAE and internationally, supporting Abu Dhabi’s broader ambitions in the life sciences sector. Fair and transparent dispute system with automated support for common issues. Many disputes can be settled between buyers and vendors without staff intervention. When staff mediation is needed, saved copies of original listings ensure accurate resolution based on the terms at time of purchase. Enhanced account security through mandatory 2FA implementation usingtime-based one-time passwords (TOTP), preventing unauthorized access even ifcredentials are compromised.
- As understanding of them improves, it is easy to see how they can benefit all stakeholders, including manufacturers, wholesalers, distributors, doctors, pharmacies, and patients.
- Preparing amphetamine for injection changes it from a Class B to a Class A drug.
- Some of those suppliers’ IDs (ie, A1CRACK and DiazNL) are neither common words nor have special meaning.
- In the above objective function, C+ is always larger than C−, which means that the penalty of misclassifying a positive instance is larger than that of a negative instance.
- Once the item is received, the buyer finalizes the purchase by notifying the anonymous online marketplace to release the funds held in escrow (step 11) [8,9].
- When interpreted by professionals, our initial results demonstrate useful findings and may be used downstream by law enforcement and public policy makers for impactful structural interventions to the opioid crisis.
- First Logevity Limited provides a service to strictly match groups or individuals seeking investment capital with individuals looking to invest.
Key Players in the Pancreatic And Bile Duct Cancer Drug Market
A hub is meant to provide better and more comprehensive patient services. But another factor that’s worthy of consideration is the way in which drug dealers and darknet vendors are diversifying their offering and creating a more reliable service—even in the face of transnational cybercrime crackdowns and rampant fraudulent activity. More people are buying their drugs on the dark web than any other time in recorded history, according to the findings of the latest Global Drug Survey (GDS).
- Our study determined the underground marketplace and forum list based on darknet site search engines and previous research works [20].
- Drug Hub operates a private Jabber server for push notifications and optional vendor communication.
- Never access Drug Hub or any darknet marketplace without proper security precautions.
- While the UAE’s hosting infrastructure offers certain advantages, it also brings the platform within the jurisdictional reach of international law enforcement.
is the regularization term, which is the L1-norm.
Links to NCBI Databases
Ultimately, Hub Services are indispensable in bridging the gap between patients and the life-saving therapies they require. As observed in our data set, the opioid suppliers in the marketplaces Evolution, Pandora, and Silk Road accepted escrow as a method of payment. In fact, the shutdown of the marketplace Evolution was discovered to be an exit scam, with the site’s operators shutting down abruptly to steal the approximately US $12 million in bitcoins that it was holding as an escrow [39]. Inspired by the work [36] investigating the supplier migration phenomenon between underground marketplaces, we also evaluated the migrant suppliers who, for the first time, began to trade in a new market, m’, after the closure of marketplace m.
📊 Market Research Intellect: Company Overview
The hub can complete benefits investigation, review formulary requirements, explore co-pay assistance offerings, and identify prior authorizations or step therapy requirements. The hub vendor specifically services this patient set and works diligently to resolve problems, thereby boosting compliance and preventing abandonment. When prescribing a specialty medication that has available hub services, a prescriber can send referrals directly to the hub. This breaks down barriers to the patient receiving medication therapy. As previously alluded, hubs were created in the 1990s mainly to assist with benefit and reimbursement services for patients and providers. Among other services, this offering continues today and is a cornerstone service of many hubs.
- Longevity biotech Juvenescence today announced the first close of its Series B-1 financing round, securing $76 million to support the continued development of its AI-driven clinical pipeline focused on age-related diseases.
- Like any marketplace, branding is key, even in the shadowy corners of the internet.
- The facilities, which the province is calling HART hubs, are part of the Progressive Conservative government’s marked shift away from harm reduction policies and toward a focus on addictions treatment and recovery.
- From our measurement, we concluded that anonymous online marketplaces and forums provided easy-access platforms for global opioid supply.
- The hub can complete benefits investigation, review formulary requirements, explore co-pay assistance offerings, and identify prior authorizations or step therapy requirements.
Drughub
To evaluate the aforementioned methods for extracting properties, we randomly chose 1000 listings for each property and manually annotated the properties as ground truth. We evaluated our method on our annotated data set, which yields an accuracy of over 90% for each property extraction, as shown in Table 5. In this way, we collected 7100 promotion posts and 6408 review posts from forum posts in total. Finally, in the model refining stage, the model is trained for other 2 iterations using the same objective function. We manually investigated the results by randomly sampling 10% of data records during each iteration and adding false positive samples into the unlabeled set.
Casey House: Supervised Inhalation
As the number one market today, we pride ourselves onour advanced escrow protection androbust security systems, ensuring every transaction remains safe and secure. Monero (XMR) is the sole payment method,providing maximum privacy and anonymity for users navigating the dark web.Launched two years ago, Drughub Market has set the standard for reliability andsecurity. Find our official onion link and verified mirror here to access ourmarketplace for an unparalleled, private browsing experience.
We sincerely thank you for your support.
That same report concluded the health ministry did not provide a thorough, evidence-based business case for the hub model and did not provide proper impact analysis or do proper consultations with all affected people. Harm reduction advocates have condemned the move to shutter supervised consumption sites, saying it will put lives at risk and only move drug use into public spaces. More than 2,600 Ontarians died in 2023 due to overdoses, the vast majority due to opioid toxicity. Supervised consumption sites impacted by the bill were given an option to apply to become HART hubs, and the nine facilities approved by the province will transition to the new model of care by March 31, the date they were slated to shut down. For example, there might be varying types of heroin or fentanyl, but we could not subcategorize them due to the lack of precise ontology. Addressing this challenge requires deep domain knowledge and expertise, which is constantly evolving.
Homeless and Addiction Recovery Treatment Hubs (HART Hubs): Reference document, January 2025
Speculation abounds that DrugHub’s servers may have already been compromised by law enforcement. If true, this would not only spell disaster for the platform’s users but also serve as a stark reminder of the stakes involved in operating within this clandestine realm. While the UAE’s hosting infrastructure offers certain advantages, it also brings the platform within the jurisdictional reach of international law enforcement. A bilateral treaty between the UAE and the United States allows for the extradition of individuals involved in criminal activities, making DrugHub’s choice of location a precarious gamble. “Frost & Sullivan identifies HUB’s epithelial tissue-based technology as groundbreaking and innovative. This award recognizes HUB at the forefront of innovation and growth in the field of organoid technology, continuously improving its offerings to meet the dynamic needs of drug developers and providing state-of-the-arts solutions.
Hamilton Urban Core Community Health Centre
Challenges include supply chain disruptions, cost volatility, and regulatory compliance pressures. CovertAction Magazine does not receive corporate or government sponsorship. Yet, we hold a steadfast commitment to providing compensation for writers, editorial and technical support.
- Specialty pharmacy providers (SPPs) are working to gain access to limited distribution medications and service patients to the best of their ability, but it is patients who can end up as victims to all of these complexities.
- The focus remains on enhancing treatment accessibility and integrating advanced therapies, positioning Bangladesh as an emerging market for pancreatic and bile duct cancer management in South Asia.
- Many new medications are earning approval with the caveat that REMS must be implemented and followed for safe patient use.
- Particularly, as shown in Table 8, the United States and the United Kingdom are always in the top 5 advertised origins among years.
- Nineteen new addiction treatment hubs will be operational in Ontario before 10 supervised consumption sites are forced to close their doors in March, the Ford government is promising.
Training Information Support
By identifying emerging trends, mapping growth opportunities, and evaluating competitive landscapes, we empower clients to navigate complex market dynamics with confidence. Unlike other markets that hide fees in vendor pricing, Drug Hub is transparent. Customers pay a standard 5% commission that can be adjusted based on account activity and volume.
🔒 Final Security Reminder
Specifically, we first conducted a whole-site crawl of anonymous online marketplaces and forums to solicit data. We then developed a suite of opioid domain–specific text mining techniques (eg, opioid jargon detection and opioid trading information retrieval) to recognize information relevant to opioid trading activities (eg, commodities, price, shipping information, and suppliers). Subsequently, we conducted a comprehensive, large-scale, longitudinal study to demystify opioid trading activities in anonymous markets and forums. Our study identified 41,000 opioid trade–related marketplace listings and forum posts by analyzing more than 1 million listings and posts in multiple anonymous marketplaces and forums, which is the largest underground opioid trading data set ever reported. We found evidence through extensive analyses of the anonymous online market of pervasive supply, which fuels the international opioid epidemic. Nontraditional methods, as presented here by studying the online supply chain, present a novel approach for governmental and other large-scale solutions.
Health Sciences North/ Horizon Santé Nord (Greater Sudbury)
Market Research Intellect (MRI) is a trusted provider of comprehensive market intelligence, delivering actionable insights that enable businesses to make informed, strategic decisions. With a focus on accuracy, depth, and relevance, we specialize in analyzing global markets across diverse industries including healthcare, technology, chemicals, consumer goods, energy, and more. Drug Hub features a unique mirror distribution system where each user receives personal mirror links. Unlike traditional marketplaces with shared backup mirrors, our system provides truly unique onion addresses for enhanced security and reliability. The government said it plans to have no gaps in care, meaning the new hubs will be open before supervised consumption sites are ordered to close by March 31, 2025.
- The platform’s creators, likely seasoned veterans of the darknet ecosystem, should have known better than to leave such glaring vulnerabilities.
- The hubs will not provide a safe supply of illicit drugs, supervised consumption services or needle exchange programs.
- Our research collected product listings and forum posts from 10 anonymous online market places and 6 forums.
- The following is a quick overview of our in-depth research report on the benefits of specialty drug Hub Services.
- The facility is also significant because it will manufacture Lilly’s highly-anticipated oral GLP-1, which is expected to receive approval in March.
- Critical security announcements are posted on the marketplace homepage and this clearnet site.
In our study, we only selected marketplaces with more than 30 opioid listings. In this way, we gathered 5 active underground marketplaces with opioid listings. Note that some high-profile underground marketplaces and forums are frequently deactivated or have been shut down by law enforcement authorities [23]. Hence, we also gathered snapshots of 5 underground marketplaces and 6 forums collected by the anonymous marketplace archives programs and previous research projects [20].
Pancreatic And Bile Duct Cancer Drug Market by Application
- This is the first study to measure and characterize opioid trading in anonymous online marketplaces and forums.
- Details of how the call for proposals for local groups to run the locations will work are set to come “later this month” with plans to begin operating the sites sometime between December 2024 and March 2025.
- Co-occurrence of the same opioid suppliers across different anonymous marketplaces.
- In relation to this idea, manufacturers are using hubs to shorten the supply chain, using logistics organizations to manage inventory and supply to appropriate pharmacies.
- Gilbert et al [15] described changes in the conceptualizations, techniques, and structures of opioid supply chains and illustrated the diversity of transactions beyond the traditionally linear conceptualizations of cartel-based distribution models.
- The focus on expanding treatment options and clinical research is expected to accelerate market growth, making Pakistan an emerging hub for pancreatic and bile duct cancer therapeutics in the region.
- Our opioid jargon identification procedure implemented a modified semantic comparison model [19].
To this end, we first collected the marketplace’s lifespan using the Gwern archive [37], as shown in Table 1, and then compared the supplier lists in each marketplace to investigate supplier migration. In addition, we observed that 10 and 9 suppliers in Apollon and Empire, respectively, migrated from Agora 3 years after it shut down. Some of those suppliers’ IDs (ie, A1CRACK and DiazNL) are neither common words nor have special meaning. Those suppliers kept using the same IDs for years to gain reputation and familiarity from buyers. Drug Hub is a revolutionary XMR-only darknet marketplace built from the ground up with security, privacy, and user experience as top priorities.
💼 Security & Trust
The government also unveiled plans to stop other supervised drug injection sites from opening in Ontario, going against its own expert advice but citing rising crime and complaints from neighbours. Nitazenes are a new synthetic opioid drug that has emerged in the UK drug supply. The hub may be there for patient education and support, co-pay assistance, pharmacy triage, or a series of other reasons. Therefore, as a partner to the patient, the hub is tasked to improve patient care and outcomes, which is something every pharmacist can get behind. While performing many duties, the hub functions to simplify the path from manufacturer to patient.
When interpreted by professionals, our initial results demonstrate useful findings and may be used downstream by law enforcement and public policy makers for impactful structural interventions to the opioid crisis. Although a large body of current research is focused on pathways for treatment of opioid use disorder and analyzing deaths per treatment capacity of substance use providers, these research areas are limited to the demand side of the opioid epidemic [40,41]. We believe that the findings and pattern analyses presented here, which place concentration on the supply side, might suggest a new direction to focus and will serve as a useful complement to current research conducted within the domain of addiction medicine. This section elaborates on the methodology used to identify opioid trading information in the anonymous market and forums. Specifically, we collected approximately 248,359 unique listings and 1,138,961 unique forum traces (ie, threads of posts) from 10 anonymous online marketplaces and 6 forums. We then identified 311 opioid keywords and jargons to recognize 28,106 listings and 13,508 forum traces related to underground opioid trading activities.
Everything’s bigger in Texas, the saying goes, and that’s true of Eli Lilly’s plans to build a new $6.5 billion manufacturing facility in Houston, marking one of the state’s biggest life sciences investments. Lilly expects the project will bring 615 high-wage jobs for drug hub market engineers, scientists, operations personnel and lab technicians, as well as 4,000 additional jobs during construction. The facility is also significant because it will manufacture Lilly’s highly-anticipated oral GLP-1, which is expected to receive approval in March.
Through their numerous services, the hub acts to assist the patient in their health care journey. In relation to this idea, manufacturers are using hubs to shorten the supply chain, using logistics organizations to manage inventory and supply to appropriate pharmacies. This management can be in the form of a partner pharmacy that works explicitly with the manufacturer or a network of pharmacies that are contracted to dispense the manufacturer’s medication. Furthermore, many hubs may administrate quick start programs that are designed to provide patients with therapy while the benefits investigation is being resolved. Boiled down to the basics, a hub is a service that allows a manufacturer to have a singular point of contact with patients who utilize their therapies.
Experienced vendors with 250+ successful sales on other established darknetmarketplaces can apply for instant approval on Drughub Market. Our verification process for the Drughub darknet includes thorough reputationchecks, transaction history reviews, and advanced security assessments. Join theDrughub dark web marketplace today tostart selling securely via our verified Drughub market onion links and official Drughub mirrors. It is comprehensive but accessible and policy-oriented, intended to facilitate discussions at EU-level on how to respond to darknet drug markets, whilst identifying key priority areas that require attention and where activities are likely to have most impact. Minister of Health Sylvia Jones has said the government plans to open 19 of the treatment hubs and 375 highly supportive housing units at a planned cost of $378 million. The hubs will not provide a safe supply of illicit drugs, supervised consumption services or needle exchange programs.
In a surprise announcement last week, Ontario Health Minister Sylvia Jones unveiled almost $380 million in funding for addiction recovery hubs, while ordering the majority of supervised drug consumption sites in the province to close their doors. Alex Toman attended Duquesne University, earning his Doctor of Pharmacy degree in 2011. Alex worked as a retail pharmacist until 2015, at which time he transitioned into a clinical pharmacist role within the specialty pharmacy industry. With these complexities, the hub can function as a liaison between the distribution channel partners and the patient. A manufacturer that develops a medication with characteristics such as limited distribution, REMS requirements, or orphan drug patient populations can greatly benefit from the services of a hub. Some hubs also employ nurses or professional personnel to travel to homes and teach patients and caregivers how to properly mix, administer, and store their medications.
Xylazine has been found in drugs across the UK and can lead to serious wounds amongst other risks. You can save a life with naloxone available for free from your local drug service. Therefore, because of the advantage that the pharmaceutical manufacturer receives for the distribution of medication, they will periodically elect to operate a hub in-house. Nevertheless, this does pose challenges and it is imperative to keep patient information away from the operations of the business. A hub that operates to maintain REMS reporting requirements can provide valuable information for these reevaluations. This can occur when benefits investigation is ongoing or when a servicing pharmacy is no longer in network.
Select products, specify quantities, and provide encrypted shippinginformation using our secure order form. Drughub Market maintains strict vendor verification to ensure marketplacequality and customer satisfaction. Drughub Market employs state-of-the-art security measures to protect yourprivacy and transactions. Paste the mirror URL in Tor browser, complete CAPTCHA verification, andcreate your secure account.
Gilbert et al [15] described changes in the conceptualizations, techniques, and structures of opioid supply chains and illustrated the diversity of transactions beyond the traditionally linear conceptualizations of cartel-based distribution models. Dasgupta et al [18] collected opioid listings on Silk Road to analyze the prices of diverted prescription opioids. Duxbury et al [6] evaluated the role of trust in online drug markets by applying exponential random graph modelling to underground marketplace transactions. The results show that vendors’ trustworthiness is a better predictor of vendor selection than product diversity or affordability. Considering social media data (eg, Twitter and Instagram), Nasralah et al [14] proposed a text mining framework to collect opioid data from social media and analyzed the most discussed topics to profile the opioid epidemic and crisis.
Otherwise, the buyer will pay the trader directly using cryptocurrency or any other payment method accepted by the trader (step 9) [7]. Note that the escrow mechanism is widely deployed in the anonymous online market because it helps to build trust and resolve disputes between sellers and buyers. When the purchase is made, the opioid trader ships the purchased item to the buyer (step 10). Once the item is received, the buyer finalizes the purchase by notifying the anonymous online marketplace to release the funds held in escrow (step 11) [8,9]. After that, an opioid buyer often leaves review comments under the product listing or discusses the purchasing experience in the forum (step 12). Welcome to Drughub Market, the premierdarknet platform crafted by the esteemed White House Market team, operatingsecurely for over 2 years.
To avoid blocking from the marketplace, we provided as an input to the scraper a session cookie that we obtained by manually logging into the marketplace and solving a Completely Automated Public Turing test to tell Computers and Humans Apart (CAPTCHA). However, some sites, namely, the Empire Market, forced users to log out when the life span of the session cookie was expired. In addition, we set parameters such as sleeping time to limit the speed of crawling.
One unsurprising consequence is that it gives consumers unprecedented ease of access to illicit—and oftentimes mysterious—substances. Each year, somewhere around a quarter to a third of GDS respondents say that they’ve consumed a wider range of drugs since using the dark web. The breadth of the darknet’s product offering, combined with the relatively low barrier to entry, creates gateways to novel drug-using behaviours, where people try new substances just because they’ve suddenly been made available to them. Drugshub.su serves as a dynamic link generator, providing short-term access in the event the principal links are not accessible. Learn how we’re keeping our communities safer and improving access to mental health through the transition of nine supervised drug injection sites into HART Hubs.